D23G (p.Asp23Gly) variant of PTPN4 (P29074)
D23G (p.Asp23Gly) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
D23G (p.Asp23Gly) variant details
- p.Asp23Gly
- rs1368451762
- gnomAD 2-119809921-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.39
- ESM-1b 0.64
- AlphaMissense 0.25
- MetaLR 0.37
- MetaSVM -0.27
- CADD 25.60
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available