A42T (p.Ala42Thr) variant of PTPN4 (P29074)
A42T (p.Ala42Thr) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
A42T (p.Ala42Thr) variant details
- p.Ala42Thr
- gnomAD 2-119809977-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.27
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.14
- MetaSVM -0.80
- CADD 21.60
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available