A21S (p.Ala21Ser) variant of PTPN4 (P29074)
A21S (p.Ala21Ser) in PTPN4 (P29074) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- Ensembl rs1558732859
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- REVEL 0.18
- ESM-1b 0.78
- AlphaMissense 0.13
- MetaLR 0.40
- MetaSVM -0.35
- CADD 25.30
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available