Y126C (p.Tyr126Cys) variant of PTPN2 (P17706)
Y126C (p.Tyr126Cys) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
Y126C (p.Tyr126Cys) variant details
- p.Tyr126Cys
- gnomAD rs1354030120
- Missense
- Variant Prioritization Score for Impact Estimate 0.836
- REVEL 0.95
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available