T86P (p.Thr86Pro) variant of PTPN2 (P17706)
T86P (p.Thr86Pro) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
T86P (p.Thr86Pro) variant details
- p.Thr86Pro
- gnomAD rs1267220108
- Missense
- Variant Prioritization Score for Impact Estimate 0.776
- REVEL 0.88
- CADD 25.90
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available