T4S (p.Thr4Ser) variant of PTPN2 (P17706)
T4S (p.Thr4Ser) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
T4S (p.Thr4Ser) variant details
- p.Thr4Ser
- TOPMed rs945467973
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.06
- CADD 6.38
- PolyPhen-2 0.00
- SIFT 0.77
- Most common in the Latino/Admixed American population (allele frequency 2.4e-05)
- Structural context available