T4N (p.Thr4Asn) variant of PTPN2 (P17706)
T4N (p.Thr4Asn) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
T4N (p.Thr4Asn) variant details
- p.Thr4Asn
- ExAC rs747486746
- gnomAD rs747486746
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.06
- CADD 7.33
- PolyPhen-2 0.00
- SIFT 0.66
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available