T3A (p.Thr3Ala) variant of PTPN2 (P17706)
T3A (p.Thr3Ala) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T3A (p.Thr3Ala) variant details
- p.Thr3Ala
- TOPMed rs1385843772
- gnomAD rs1385843772
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.01
- CADD 8.47
- PolyPhen-2 0.00
- SIFT 0.73
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available