T14S (p.Thr14Ser) variant of PTPN2 (P17706)
T14S (p.Thr14Ser) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T14S (p.Thr14Ser) variant details
- p.Thr14Ser
- gnomAD rs1184779249
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.11
- CADD 16.10
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 4.8e-05)
- Structural context available