T139A (p.Thr139Ala) variant of PTPN2 (P17706)
T139A (p.Thr139Ala) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
T139A (p.Thr139Ala) variant details
- p.Thr139Ala
- gnomAD rs1400124644
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- REVEL 0.47
- CADD 22.40
- PolyPhen-2 0.03
- SIFT 0.09
- Most common in the Middle Eastern population (allele frequency 0.00019)
- Structural context available