S142T (p.Ser142Thr) variant of PTPN2 (P17706)
S142T (p.Ser142Thr) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S142T (p.Ser142Thr) variant details
- p.Ser142Thr
- TOPMed rs1213254112
- gnomAD rs1213254112
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.19
- CADD 10.30
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available