P20S (p.Pro20Ser) variant of PTPN2 (P17706)
P20S (p.Pro20Ser) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P20S (p.Pro20Ser) variant details
- p.Pro20Ser
- TOPMed rs1361746465
- gnomAD rs1361746465
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.03
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 0.76
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available