N63S (p.Asn63Ser) variant of PTPN2 (P17706)
N63S (p.Asn63Ser) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
N63S (p.Asn63Ser) variant details
- p.Asn63Ser
- TOPMed rs996337306
- gnomAD rs996337306
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.17
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available