L12F (p.Leu12Phe) variant of PTPN2 (P17706)
L12F (p.Leu12Phe) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
L12F (p.Leu12Phe) variant details
- p.Leu12Phe
- Ensembl rs867997369
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.03
- CADD 22.40
- PolyPhen-2 0.06
- SIFT 0.05
- Population evidence available
- Structural context available