K105N (p.Lys105Asn) variant of PTPN2 (P17706)
K105N (p.Lys105Asn) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
K105N (p.Lys105Asn) variant details
- p.Lys105Asn
- TOPMed rs2042648239
- gnomAD rs2042648239
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.22
- CADD 19.50
- PolyPhen-2 0.02
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available