I69V (p.Ile69Val) variant of PTPN2 (P17706)
I69V (p.Ile69Val) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
I69V (p.Ile69Val) variant details
- p.Ile69Val
- Ensembl rs2042883173
- Missense
- Variant Prioritization Score for Impact Estimate 0.665
- REVEL 0.69
- CADD 25.00
- PolyPhen-2 0.89
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available