F97L (p.Phe97Leu) variant of PTPN2 (P17706)
F97L (p.Phe97Leu) in PTPN2 (P17706) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
F97L (p.Phe97Leu) variant details
- p.Phe97Leu
- ExAC rs768576389
- TOPMed rs768576389
- gnomAD rs768576389
- Missense
- Variant Prioritization Score for Impact Estimate 0.672
- REVEL 0.82
- CADD 26.70
- PolyPhen-2 0.86
- SIFT 0.04
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available