M32T (p.Met32Thr) variant of PTH1R (Q03431)
M32T (p.Met32Thr) in PTH1R (Q03431) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
M32T (p.Met32Thr) variant details
- p.Met32Thr
- NCI-TCGA Cosmic COSV5731
- cosmic curated COSV57314
- gnomAD rs2031579553
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.08
- CADD 24.10
- PolyPhen-2 0.00
- SIFT 0.03
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available