M11T (p.Met11Thr) variant of PTH (Parathyroid hormone)
M11T (p.Met11Thr) in PTH (Parathyroid hormone) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
M11T (p.Met11Thr) variant details
- p.Met11Thr
- gnomAD rs1847492713
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.30
- MetaLR 0.39
- MetaSVM -0.75
- CADD 16.30
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available