G34G (p.Gly34Gly) variant of PSEN2 (Presenilin-2)
G34G (p.Gly34Gly) in PSEN2 (Presenilin-2) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
G34G (p.Gly34Gly) variant details
- p.Gly34Gly
- gnomAD 1-226882009-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.397
- CADD 14.10
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available