Y80H (p.Tyr80His) variant of PROS1 (Vitamin K-dependent protein S)
Y80H (p.Tyr80His) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data.
Y80H (p.Tyr80His) variant details
- p.Tyr80His
- ESP rs145704559
- ExAC rs145704559
- TOPMed rs145704559
- gnomAD rs145704559
- Missense
- Variant Prioritization Score for Impact Estimate 0.715
- REVEL 0.84
- CADD 26.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)