V18G (p.Val18Gly) variant of PROS1 (Vitamin K-dependent protein S)
V18G (p.Val18Gly) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data.
V18G (p.Val18Gly) variant details
- p.Val18Gly
- TOPMed rs1162049144
- gnomAD rs1162049144
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- REVEL 0.43
- CADD 14.90
- PolyPhen-2 0.13
- SIFT 0.06
- Most common in the South Asian population (allele frequency 1.2e-05)