T49S (p.Thr49Ser) variant of PROS1 (Vitamin K-dependent protein S)
T49S (p.Thr49Ser) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data.
T49S (p.Thr49Ser) variant details
- p.Thr49Ser
- gnomAD rs1386488557
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.29
- CADD 11.00
- Most common in the African/African-American population (allele frequency 2.4e-05)