S91C (p.Ser91Cys) variant of PROS1 (Vitamin K-dependent protein S)
S91C (p.Ser91Cys) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data.
S91C (p.Ser91Cys) variant details
- p.Ser91Cys
- gnomAD rs1411206237
- Missense
- Variant Prioritization Score for Impact Estimate 0.551
- REVEL 0.62
- AlphaMissense 0.12
- MetaLR 0.97
- MetaSVM 1.02
- CADD 21.90
- PolyPhen-2 0.84
- Most common in the REMAINING population (allele frequency 1.7e-05)