R69T (p.Arg69Thr) variant of PROS1 (Vitamin K-dependent protein S)
R69T (p.Arg69Thr) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data.
R69T (p.Arg69Thr) variant details
- p.Arg69Thr
- gnomAD rs1709033270
- Missense
- Variant Prioritization Score for Impact Estimate 0.856
- REVEL 0.93
- CADD 25.50
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)