Q120K (p.Gln120Lys) variant of PROS1 (Vitamin K-dependent protein S)
Q120K (p.Gln120Lys) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data.
Q120K (p.Gln120Lys) variant details
- p.Gln120Lys
- TOPMed rs1471724817
- gnomAD rs1471724817
- Missense
- Variant Prioritization Score for Impact Estimate 0.744
- REVEL 0.71
- CADD 26.30
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)