N115S (p.Asn115Ser) variant of PROS1 (Vitamin K-dependent protein S)
N115S (p.Asn115Ser) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data.
N115S (p.Asn115Ser) variant details
- p.Asn115Ser
- TOPMed rs1021844343
- gnomAD rs1021844343
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.17
- CADD 12.10
- PolyPhen-2 0.03
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 2.4e-05)