L110R (p.Leu110Arg) variant of PROS1 (Vitamin K-dependent protein S)
L110R (p.Leu110Arg) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data.
L110R (p.Leu110Arg) variant details
- p.Leu110Arg
- Ensembl rs1708746146
- Missense
- Variant Prioritization Score for Impact Estimate 0.753
- REVEL 0.82
- CADD 28.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 4.6e-05)