I59V (p.Ile59Val) variant of PROS1 (Vitamin K-dependent protein S)
I59V (p.Ile59Val) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
I59V (p.Ile59Val) variant details
- p.Ile59Val
- Ensembl rs1709033990
- Missense
- Variant Prioritization Score for Impact Estimate 0.398
- REVEL 0.46
- CADD 21.90
- PolyPhen-2 0.64
- SIFT 0.58
- Most common in the East Asian population (allele frequency 2.5e-05)