G6R (p.Gly6Arg) variant of PROS1 (Vitamin K-dependent protein S)
G6R (p.Gly6Arg) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data.
G6R (p.Gly6Arg) variant details
- p.Gly6Arg
- ExAC rs775508221
- gnomAD rs775508221
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.19
- CADD 13.90
- PolyPhen-2 0.01
- SIFT 0.31
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)