G5S (p.Gly5Ser) variant of PROS1 (Vitamin K-dependent protein S)
G5S (p.Gly5Ser) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data.
G5S (p.Gly5Ser) variant details
- p.Gly5Ser
- ExAC rs763043055
- gnomAD rs763043055
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.14
- CADD 5.35
- PolyPhen-2 0.01
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 9e-07)