F26V (p.Phe26Val) variant of PROS1 (Vitamin K-dependent protein S)
F26V (p.Phe26Val) in PROS1 (Vitamin K-dependent protein S) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data.
F26V (p.Phe26Val) variant details
- p.Phe26Val
- ExAC rs753590699
- gnomAD rs753590699
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.52
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.25
- Most common in the African/African-American population (allele frequency 3e-05)