F46del (p.Phe46del) variant of PROC (Vitamin K-dependent protein C)
F46del (p.Phe46del) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
F46del (p.Phe46del) variant details
- gnomAD 2-127421346-CCTT-
- Inframe Deletion
- Variant Prioritization Score for Impact Estimate 0.584
- CADD 15.50
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available