W83* (p.Trp83Ter) variant of PROC (Vitamin K-dependent protein C)
W83* (p.Trp83Ter) in PROC (Vitamin K-dependent protein C) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
W83* (p.Trp83Ter) variant details
- p.Trp83Ter
- ExAC rs747236088
- TOPMed rs747236088
- gnomAD rs747236088
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.765
- CADD 49.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available