V76G (p.Val76Gly) variant of PROC (Vitamin K-dependent protein C)
V76G (p.Val76Gly) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
V76G (p.Val76Gly) variant details
- p.Val76Gly
- gnomAD 2-127421439-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.50
- CADD 20.40
- PolyPhen-2 0.42
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available