T5R (p.Thr5Arg) variant of PROC (Vitamin K-dependent protein C)
T5R (p.Thr5Arg) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
T5R (p.Thr5Arg) variant details
- p.Thr5Arg
- Ensembl rs759805372
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.42
- CADD 6.84
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available