T13P (p.Thr13Pro) variant of PROC (Vitamin K-dependent protein C)
T13P (p.Thr13Pro) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
T13P (p.Thr13Pro) variant details
- p.Thr13Pro
- ExAC rs781386476
- gnomAD rs781386476
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.52
- CADD 15.80
- PolyPhen-2 0.28
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available