S53G (p.Ser53Gly) variant of PROC (Vitamin K-dependent protein C)
S53G (p.Ser53Gly) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
S53G (p.Ser53Gly) variant details
- p.Ser53Gly
- gnomAD 2-127421369-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.38
- CADD 1.86
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available