S29G (p.Ser29Gly) variant of PROC (Vitamin K-dependent protein C)
S29G (p.Ser29Gly) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
S29G (p.Ser29Gly) variant details
- p.Ser29Gly
- gnomAD rs1433394075
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.46
- CADD 23.20
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available