R57R (p.Arg57Arg) variant of PROC (Vitamin K-dependent protein C)
R57R (p.Arg57Arg) in PROC (Vitamin K-dependent protein C) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
R57R (p.Arg57Arg) variant details
- p.Arg57Arg
- gnomAD 2-127421381-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.63
- CADD 5.87
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available