R42R (p.Arg42Arg) variant of PROC (Vitamin K-dependent protein C)
R42R (p.Arg42Arg) in PROC (Vitamin K-dependent protein C) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
R42R (p.Arg42Arg) variant details
- p.Arg42Arg
- rs1459858777
- gnomAD 2-127421338-T-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0824
- CADD 0.28
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available