Q35H (p.Gln35His) variant of PROC (Vitamin K-dependent protein C)
Q35H (p.Gln35His) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
Q35H (p.Gln35His) variant details
- p.Gln35His
- ExAC rs754445822
- gnomAD rs754445822
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.26
- CADD 18.40
- PolyPhen-2 0.02
- SIFT 0.07
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available