P20S (p.Pro20Ser) variant of PROC (Vitamin K-dependent protein C)
P20S (p.Pro20Ser) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
P20S (p.Pro20Ser) variant details
- p.Pro20Ser
- gnomAD 2-127420000-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.20
- CADD 10.30
- PolyPhen-2 0.00
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available