G15E (p.Gly15Glu) variant of PROC (Vitamin K-dependent protein C)
G15E (p.Gly15Glu) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
G15E (p.Gly15Glu) variant details
- p.Gly15Glu
- gnomAD 2-127419986-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.36
- CADD 17.70
- PolyPhen-2 0.01
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available