F46F (p.Phe46Phe) variant of PROC (Vitamin K-dependent protein C)
F46F (p.Phe46Phe) in PROC (Vitamin K-dependent protein C) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
F46F (p.Phe46Phe) variant details
- p.Phe46Phe
- rs141040323
- gnomAD 2-127421350-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.267
- CADD 6.66
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available