E61K (p.Glu61Lys) variant of PROC (Vitamin K-dependent protein C)
E61K (p.Glu61Lys) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data, published literature, and structural context.
E61K (p.Glu61Lys) variant details
- p.Glu61Lys
- gnomAD 2-127421393-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.852
- REVEL 0.90
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available