D65N (p.Asp65Asn) variant of PROC (Vitamin K-dependent protein C)
D65N (p.Asp65Asn) in PROC (Vitamin K-dependent protein C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
D65N (p.Asp65Asn) variant details
- p.Asp65Asn
- gnomAD rs1287265930
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.35
- CADD 20.70
- PolyPhen-2 0.30
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available