W73* (p.Trp73Ter) variant of PRNP (Major prion protein)
W73* (p.Trp73Ter) in PRNP (Major prion protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data, published literature, and structural context.
W73* (p.Trp73Ter) variant details
- p.Trp73Ter
- gnomAD 20-4699438-G-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.826
- CADD 36.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available