T33P (p.Thr33Pro) variant of PRNP (Major prion protein)
T33P (p.Thr33Pro) in PRNP (Major prion protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
T33P (p.Thr33Pro) variant details
- p.Thr33Pro
- ExAC rs767032162
- Missense
- Variant Prioritization Score for Impact Estimate 0.475
- REVEL 0.51
- CADD 24.70
- Most common in the HGDP:BASQUE population (allele frequency 0.023)
- Structural context available