R37* (p.Arg37Ter) variant of PRNP (Major prion protein)
R37* (p.Arg37Ter) in PRNP (Major prion protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
R37* (p.Arg37Ter) variant details
- p.Arg37Ter
- ExAC rs11538763
- gnomAD rs11538763
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.677
- CADD 36.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available